A new peer-review paper assesses the interest of Nor-Grape® BP-O in dairy cows

The research shows that supplemented cows had better milk production with equivalent milk quality
calendar icon 30 July 2025
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Nor-Feed is pleased to announce the publication of a new peer-reviewed study in the Journal of Dairy Science, highlighting the positive effects on dairy cows of Nor-Grape® BP-O, which selected and rumino-protected grape polyphenols potentiate antioxidant defenses.

The research shows that supplemented cows had better milk production with equivalent milk quality while ensuring their comfort under heat stress. Heat stress is, more than ever, a pressing issue and casts a shadow over the performance and profitability of dairy production.

The dairy cows supplemented with Nor-Grape® BP-O exhibited significant enhancements in several key areas compared to the ones in the control group, such as:

  • +1.8 kg/day of milk with the same solids content
  • Improved thermoregulatory responses with lower rectal temperatures and reduced heavy breathing
  • Enhanced innate immune responses with higher neutrophil efficiency
  • Better ruminal function seen by lower circulating level of urea and creatinin
  • Lower liver damages assessed by circulating level of GGT and bilirubin

This means better cow comfort, metabolic efficiency, and milk quantity in the toughest summer conditions.

Nor-Grape® BP-O is 100% natural and is standardized in polyphenols extracted from grape. This solution provides water-soluble physiological antioxidants. Grape polyphenols from Nor-Grape® BP-O potentiate the animal’s antioxidant defences. Nor-Grape® BP-O is based on a specific by-pass formulation.

Special thanks to Annalisa Amato, Vincenzo Lopreiato and their team, our partners from University of Messina on our rich collaboration. Their outstanding work on this publication that deepen our understanding of selected grape polyphenols’ actions on animals’ physiology and productivity.

Finally, congratulations to Dr. Paul Engler, PhD and Dr. Hoa BUI, DVM for their work within Nor-Feed.

Read the publication

Laurence Williams

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